Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GCGR | P47871 | 10/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HMGCR | P04035 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9753703 | 0.90 | GCGR (0.36) | ALDH1A1GCGRPTGS2NPC1RAB9A | |
| SCHEMBL9753707 | 0.90 | GCGR (0.36) | ALDH1A1GCGRPTGS2NPC1RAB9A | |
| SCHEMBL9753393 | 0.86 | HMGCR (0.38) | ALDH1A1GCGRPTGS2HMGCR | |
| SCHEMBL9752903 | 0.82 | MAPK14 (0.43) | ALDH1A1GCGRPTGS2NPC1RAB9A | |
| SCHEMBL27346853 | 0.82 | PPARA (0.41) | ALDH1A1GCGRPTGS2NPC1RAB9A | |
| SCHEMBL9753342 | 0.81 | GCGR (0.55) | GCGR | |
| SCHEMBL9752971 | 0.81 | PTGS2 (0.39) | ALDH1A1PTGS2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9753077 | 0.78 | ALDH1A1 (0.44) | ALDH1A1GCGRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9753784 | 0.78 | HMGCR (0.47) | ALDH1A1HMGCR | |
| SCHEMBL9753373 | 0.78 | HMGCR (0.60) | ALDH1A1PTGS2HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018903-A1 | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-12 | — | — | WO | disclosed |
| CN-1056690-A | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO (JP) | 1991-12-04 | — | — | CN | disclosed |