Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9752856 | 0.99 | PKM (0.44) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL13699279 | 0.87 | CA12 (0.50) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL13699280 | 0.87 | CA12 (0.50) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL13699375 | 0.87 | CA12 (0.50) | ALDH1A1MEN1KMT2APOLBPKM | |
| Hydrochloric Acid SCHEMBL9752703 | 0.86 | CPB1 (0.46) | ALDH1A1POLBMAPTCTSK | |
| SCHEMBL9753427 | 0.81 | MFN2 (0.42) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL9752791 | 0.79 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL9752792 | 0.79 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL9753211 | 0.79 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL6942075 | 0.77 | SMYD3 (0.40) | ALDH1A1POLBL3MBTL1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991007378-A1 | CYCLOALKYL-SUBSTITUTED GLUTARAMIDE DIURETIC AGENTS | PFIZER LIMITED (GB) | 1991-05-30 | — | — | WO | disclosed |