Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6942075 | 0.77 | SMYD3 (0.40) | ALDH1A1SMN1; SMN2POLBTSHRL3MBTL1 | |
| SCHEMBL6942077 | 0.77 | SMYD3 (0.40) | ALDH1A1SMN1; SMN2POLBTSHRL3MBTL1 | |
| SCHEMBL9753431 | 0.77 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1POLBL3MBTL1 | |
| Hydrochloric Acid SCHEMBL9752856 | 0.76 | PKM (0.44) | MEN1KMT2AALDH1A1POLBL3MBTL1 | |
| Hydrochloric Acid SCHEMBL28748271 | 0.76 | SMYD3 (0.39) | ALDH1A1POLBL3MBTL1 | |
| Hydrochloric Acid SCHEMBL9752801 | 0.74 | SMYD3 (0.37) | ALDH1A1KDM4EPOLBTSHRL3MBTL1 | |
| SCHEMBL9753054 | 0.74 | SMYD3 (0.37) | ALDH1A1POLBTSHRL3MBTL1 | |
| Hydrochloric Acid SCHEMBL9753080 | 0.73 | SMYD3 (0.36) | ALDH1A1POLBTSHRL3MBTL1 | |
| SCHEMBL6643050 | 0.70 | SMN1; SMN2 (0.63) | HSD17B10MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL6335581 | 0.69 | SMN1; SMN2 (0.66) | HSD17B10MEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991007378-A1 | CYCLOALKYL-SUBSTITUTED GLUTARAMIDE DIURETIC AGENTS | PFIZER LIMITED (GB) | 1991-05-30 | — | — | WO | disclosed |