Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4170301 | 0.82 | ATM (0.42) | KDM4ENPSR1POLBALDH1A1LMNA | |
| SCHEMBL14525220 | 0.76 | HTR1A (0.32) | NPSR1ALDH1A1HPGDPDE10APARP1 | |
| SCHEMBL13741144 | 0.76 | ADORA2A (0.43) | KDM4ENPSR1POLBPABPC1ALDH1A1 | |
| SCHEMBL23213942 | 0.75 | ALDH1A1 (0.40) | KDM4ENPSR1ALDH1A1LMNAHPGD | |
| SCHEMBL29844628 | 0.75 | ALDH1A1 (0.40) | KDM4ENPSR1ALDH1A1LMNAHPGD | |
| SCHEMBL26937832 | 0.75 | ALDH1A1 (0.40) | KDM4ENPSR1ALDH1A1LMNATSHR | |
| SCHEMBL9651921 | 0.72 | PGK1 (0.43) | KDM4EPOLBALDH1A1TSHRHPGD | |
| SCHEMBL10565518 | 0.72 | CYP1A2 (0.50) | POLBALDH1A1TSHRPDE10ATDP1 | |
| SCHEMBL10129558 | 0.71 | MAPK8 (0.45) | KDM4ELMNAMEN1KMT2AMAPK8 | |
| SCHEMBL7895323 | 0.70 | MAPK8 (0.59) | KDM4ENPSR1POLBLMNAMAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991017979-A1 | PROCESS FOR THE PREPARATION OF 2-N-ACYLAMINOPYRIDINES AND 2-AMINOPYRIDINES FROM 5-OXOALKANENITRILE OXIMES | DSM N.V. (NL) | 1991-11-28 | — | — | WO | disclosed |