Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 5/20 | 0.39 |
| ▸ | PGK2 | P07205 | 5/20 | 0.39 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8608425 | 0.84 | LMNA (0.37) | METTL3 | |
| SCHEMBL9753435 | 0.76 | ALDH1A1 (0.35) | — | |
| SCHEMBL8607292 | 0.75 | MAP3K5 (0.32) | PGK1PGK2METTL3 | |
| SCHEMBL8608438 | 0.73 | S1PR2 (0.34) | METTL3 | |
| SCHEMBL8605684 | 0.72 | PGK1 (0.32) | PGK1PGK2METTL3 | |
| SCHEMBL8607526 | 0.72 | KDM4E (0.47) | — | |
| SCHEMBL8606700 | 0.72 | MAP3K5 (0.37) | PGK1PGK2METTL3 | |
| SCHEMBL8607530 | 0.71 | KDM6B (0.39) | METTL3 | |
| SCHEMBL9753578 | 0.70 | ALDH1A1 (0.32) | — | |
| SCHEMBL8609515 | 0.70 | GRIN2D (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0436831-A2 | Imidazo[1,2-a]pyridinylalkyl compounds for treatment of neurotoxic injury | G.D. Searle & Co. (US) | 1991-07-17 | — | — | EP | claimed |
| WO-1991008211-A1 | IMIDAZO[1,2-a]PYRIDINYLALKYL COMPOUNDS FOR TREATMENT OF NEUROTOXIC INJURY | G.D. SEARLE & CO. (US) | 1991-06-13 | — | — | WO | claimed |
| EP-0436831-A2 | Imidazo[1,2-a]pyridinylalkyl compounds for treatment of neurotoxic injury | G.D. Searle & Co. (US) | 1991-07-17 | — | — | EP | disclosed |
| WO-1991008211-A1 | IMIDAZO[1,2-a]PYRIDINYLALKYL COMPOUNDS FOR TREATMENT OF NEUROTOXIC INJURY | G.D. SEARLE & CO. (US) | 1991-06-13 | — | — | WO | disclosed |