Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 5/20 | 0.37 |
| ▸ | CA1 | P00915 | 5/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 4/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CTSK | P43235 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9752887 | 0.95 | TDP1 (0.37) | TDP1CA2CA1CA7MAOA | |
| SCHEMBL28363958 | 0.84 | TSHR (0.54) | TDP1CA2CA1CA7MAOA | |
| SCHEMBL7119549 | 0.84 | TDP1 (0.50) | TDP1CA2CA1CA7MAOA | |
| SCHEMBL1638343 | 0.84 | CTSK (0.43) | TDP1CA2CA1CA7MAOA | |
| SCHEMBL2433806 | 0.83 | TSHR (0.38) | TDP1CA2CA1CA7MAOA | |
| SCHEMBL28651273 | 0.83 | HDAC4 (0.40) | TDP1CA2CA1CA7MAOA | |
| SCHEMBL4653239 | 0.83 | DGKA (0.43) | TDP1CA1CA7CA12CA14 | |
| SCHEMBL7279153 | 0.83 | TSHR (0.50) | TDP1CA2CA1CA7MAOA | |
| SCHEMBL25438156 | 0.81 | DGKA (0.46) | TDP1CTSKTSHR | |
| SCHEMBL20503257 | 0.81 | DGKA (0.46) | TDP1CTSKTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991008737-A2 | PHARMACOLOGICALLY ACTIVE AMIDE CARBOXYLATE DERIVATIVES | FISONS PLC (GB) | 1991-06-27 | — | — | WO | disclosed |