Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 2/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | NOS2 | P35228 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL868367 | 0.84 | AKR1C3 (0.41) | CYP11B1CYP11B2CHRNB2CHRNA4AKR1C3 | |
| SCHEMBL20538855 | 0.76 | CHRNB2 (0.39) | CYP11B1CYP11B2CHRNB2CHRNA4NOS3 | |
| SCHEMBL9406877 | 0.76 | MEN1 (0.34) | CYP11B1CYP11B2AKR1C3IDO1 | |
| SCHEMBL2728642 | 0.75 | KLKB1 (0.37) | CHRNB2CHRNA4 | |
| SCHEMBL15309539 | 0.71 | GRM5 (0.38) | CYP11B1CYP11B2 | |
| SCHEMBL18815407 | 0.70 | DRD2 (0.41) | CHRNB2CHRNA4NOS3NOS1NOS2 | |
| SCHEMBL31403551 | 0.70 | CYP11B1 (0.35) | CYP11B1CYP11B2AKR1C3 | |
| SCHEMBL20538854 | 0.70 | SIRT1 (0.37) | CHRNB2CHRNA4 | |
| SCHEMBL18816757 | 0.68 | CHRNB2 (0.41) | CYP11B1CYP11B2CHRNB2CHRNA4DRD2 | |
| SCHEMBL18794973 | 0.68 | CHRNB2 (0.41) | CYP11B1CYP11B2CHRNB2CHRNA4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991017979-A1 | PROCESS FOR THE PREPARATION OF 2-N-ACYLAMINOPYRIDINES AND 2-AMINOPYRIDINES FROM 5-OXOALKANENITRILE OXIMES | DSM N.V. (NL) | 1991-11-28 | — | — | WO | disclosed |