Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.67 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.63 |
| ▸ | HRH1 | P35367 | 2/20 | 0.62 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.54 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5791734 | 1.00 | TAAR1 (0.67) | TAAR1RIPK1HRH1AOC3HTR2A | |
| SCHEMBL1281 | 1.00 | TAAR1 (0.67) | TAAR1RIPK1HRH1AOC3HTR2A | |
| SCHEMBL23336071 | 1.00 | TAAR1 (0.67) | TAAR1RIPK1HRH1AOC3HTR2A | |
| SCHEMBL11489693 | 0.87 | CHRNB2 (0.53) | TAAR1RIPK1HRH1AOC3 | |
| SCHEMBL2096805 | 0.86 | HRH1 (0.65) | TAAR1RIPK1HRH1AOC3HTR2A | |
| Hydrochloric Acid SCHEMBL11496246 | 0.86 | CHRNB2 (0.52) | TAAR1RIPK1HRH1AOC3 | |
| SCHEMBL6280516 | 0.85 | RIPK1 (0.67) | TAAR1RIPK1AOC3TRPA1 | |
| SCHEMBL3428511 | 0.85 | TAAR1 (0.59) | TAAR1RIPK1HRH1AOC3HTR2A | |
| SCHEMBL14387157 | 0.85 | TAAR1 (0.59) | TAAR1RIPK1HRH1AOC3HTR2A | |
| SCHEMBL14459040 | 0.83 | TAAR1 (0.57) | TAAR1RIPK1HRH1AOC3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4188932-A1 | COMPOUNDS | The Provost, Fellows, Foundation Scholars and the other members of Board, of the College of the Holy and Undivided Trinity of Queen Elizabeth, (IE) | 2023-06-07 | — | — | EP | disclosed |
| WO-2022023438-A1 | COMPOUNDS | THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH, NEAR DUBLIN (IE) | 2022-02-03 | — | — | WO | disclosed |
| EP-3849969-A1 | INDAZOLE CARBOXAMIDES AS KINASE INHIBITORS | Bristol-Myers Squibb Company (US) | 2021-07-21 | — | — | EP | disclosed |
| EP-3704118-A1 | AMINOIMIDAZOPYRIDAZINES AS KINASE INHIBITORS | Bristol-Myers Squibb Company (US) | 2020-09-09 | — | — | EP | disclosed |
| WO-2020056074-A1 | INDAZOLE CARBOXAMIDES AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-03-19 | — | — | WO | disclosed |
| WO-2018148626-A1 | AMINOTRIAZOLOPYRIDINES AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-08-16 | — | — | WO | disclosed |
| EP-3307880-A1 | TRANSAMINASES | c-LEcta GmbH (DE) | 2018-04-18 | — | — | EP | disclosed |
| WO-2016198660-A1 | TRANSAMINASES | C-LECTA GMBH (DE) | 2016-12-15 | — | — | WO | disclosed |
| EP-2675774-A1 | PRODUCTION METHOD OF OPTICALLY ACTIVE DIHYDROBENZOFURAN DERIVATIVE | Takeda Pharmaceutical Company Limited (JP) | 2013-12-25 | — | — | EP | disclosed |
| WO-2012111849-A1 | PRODUCTION METHOD OF OPTICALLY ACTIVE DIHYDROBENZOFURAN DERIVATIVE | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-08-23 | — | — | WO | disclosed |
| WO-1991019002-A1 | A PROCESS FOR CHIRAL ENRICHMENT OF ASYMMETRIC PRIMARY AMINES | CARLBIOTECH LTD. A/S (DK) | 1991-12-12 | — | — | WO | disclosed |