Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.67 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.63 |
| ▸ | HRH1 | P35367 | 2/20 | 0.62 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.54 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5791734 | 1.00 | TAAR1 (0.67) | TAAR1RIPK1HRH1AOC3HTR2A | |
| SCHEMBL23336071 | 1.00 | TAAR1 (0.67) | TAAR1RIPK1HRH1AOC3HTR2A | |
| SCHEMBL9753640 | 1.00 | TAAR1 (0.67) | TAAR1RIPK1HRH1AOC3HTR2A | |
| SCHEMBL11489693 | 0.87 | CHRNB2 (0.53) | TAAR1RIPK1HRH1AOC3 | |
| SCHEMBL2096805 | 0.86 | HRH1 (0.65) | TAAR1RIPK1HRH1AOC3HTR2A | |
| Hydrochloric Acid SCHEMBL11496246 | 0.86 | CHRNB2 (0.52) | TAAR1RIPK1HRH1AOC3 | |
| SCHEMBL6280516 | 0.85 | RIPK1 (0.67) | TAAR1RIPK1AOC3TRPA1 | |
| SCHEMBL3428511 | 0.85 | TAAR1 (0.59) | TAAR1RIPK1HRH1AOC3HTR2A | |
| SCHEMBL14387157 | 0.85 | TAAR1 (0.59) | TAAR1RIPK1HRH1AOC3HTR2A | |
| SCHEMBL14459040 | 0.83 | TAAR1 (0.57) | TAAR1RIPK1HRH1AOC3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 270 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117110493-A | Metabolic marker associated with neonatal pneumonia and metabolic acidosis and application thereof | 大连大学 | 2023-11-24 | — | — | CN | claimed |
| CN-116893237-A | Metabolic marker related to neonatal pneumonia and myocardial damage and application thereof | 大连大学 | 2023-10-17 | — | — | CN | claimed |
| CN-113264895-B | Synthetic method for preparing benzoxazole compound from catechol compound and amine compound | 湖南第一师范学院 | 2022-03-25 | — | — | CN | claimed |
| CN-113264895-A | Synthetic method for preparing benzoxazole compound from catechol compound and amine compound | 湖南第一师范学院 | 2021-08-17 | — | — | CN | claimed |
| EP-3548489-A1 | ORTHO SUBSTITUTED PHENYLPYRAZOLO- AND PHENYLPYRROLO-PYRIDAZINE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2019-10-09 | — | — | EP | claimed |
| WO-2018100045-A1 | ORTHO SUBSTITUTED PHENYLPYRAZOLO- AND PHENYLPYRROLO-PYRIDAZINE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2018-06-07 | — | — | WO | claimed |
| WO-2017098520-A1 | PROCESS FOR THE PREPARATION OF LABETALOL HYDROCHLORIDE | prscDAVALURI RAMAMOHAN RAO (IN) | 2017-06-15 | — | — | WO | claimed |
| EP-3160465-A1 | USE OF SMALL MOLECULES FOR THE TREATMENT OF CLOSTRIDIUM DIFFICILE TOXICITY | The Board of Trustees of the Leland Stanford Junior University (US) | 2017-05-03 | — | — | EP | claimed |
| WO-2015200358-A1 | USE OF SMALL MOLECULES FOR THE TREATMENT OF CLOSTRIDIUM DIFFICILE TOXICITY | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2015-12-30 | — | — | WO | claimed |
| US-20120190680-A1 | Heteroaryl Amide Analogues | H. LUNDBECK A/S (DK) | 2012-07-26 | — | — | US | claimed |
| WO-2009108551-A2 | HETEROARYL AMIDE ANALOGUES | H. LUNDBECK A/S (DK) | 2009-09-03 | — | — | WO | claimed |
| WO-2009023623-A1 | HETEROARYL AMIDE ANALOGUES | H, LUNDBECK A/S (DK) | 2009-02-19 | — | — | WO | claimed |
| EP-1981831-A2 | KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF | Vaidya, Niteen A. (US) | 2008-10-22 | — | — | EP | claimed |
| EP-1934193-A1 | BENZOTHIADIAZOLYPHENYLALKYLAMINE DERIVATIVES FOR USE IN THE TREATMENT OF CONDITIONS AMELIORATED BY MONOAMINE REUPTAKE | Wyeth a Corporation of the State of Delaware (US) | 2008-06-25 | — | — | EP | claimed |
| WO-2007092264-A2 | KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF | VAIDYA NITEEN A (US) | 2007-08-16 | — | — | WO | claimed |
| WO-2007041258-A1 | BENZOTHIADIAZOLYPHENYLALKYLAMINE DERIVATIVES FOR USE IN THE TREATMENT OF CONDITIONS AMELIORATED BY MONOAMINE REUPTAKE | WYETH (US) | 2007-04-12 | — | — | WO | claimed |
| WO-2002022801-A9 | MAMMALIAN RECEPTOR GENES AND USES | UNIV OREGON HEALTH & SCIENCE (US) | 2003-07-03 | — | — | WO | claimed |
| CN-1343024-A | Organic amine used as additive in electrochemical battery | MERCK PATENT GMBH (DE) | 2002-04-03 | — | — | CN | claimed |
| EP-1187244-A2 | Organic amines as additives for electrochemical cells | MERCK PATENT GmbH (DE) | 2002-03-13 | — | — | EP | claimed |
| WO-1991019002-A1 | A PROCESS FOR CHIRAL ENRICHMENT OF ASYMMETRIC PRIMARY AMINES | CARLBIOTECH LTD. A/S (DK) | 1991-12-12 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120190680-A1 | Heteroaryl Amide Analogues | P2RX3, P2RX2, ADORA2A | TAAR1 162/4885RIPK1 1722/4885HRH1 302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.