Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.34 |
| ▸ | PGK1 | P00558 | 4/20 | 0.32 |
| ▸ | PGK2 | P07205 | 4/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8608456 | 0.80 | PTGS1 (0.36) | FBP1GAAKDM4EGLAHPGD | |
| SCHEMBL8606880 | 0.79 | PGK1 (0.42) | FBP1PGK1PGK2GAA | |
| SCHEMBL8606782 | 0.78 | PTGS1 (0.49) | GAAKDM4ENPC1 | |
| SCHEMBL9753823 | 0.78 | PGK1 (0.38) | FBP1PGK1PGK2 | |
| SCHEMBL9753860 | 0.77 | PGK1 (0.51) | PGK1PGK2GAAKDM4ENPC1 | |
| SCHEMBL8605305 | 0.77 | ALDH1A1 (0.33) | GAAKDM4EALDH1A1 | |
| SCHEMBL8608520 | 0.75 | PGK1 (0.32) | PGK1PGK2GAA | |
| Methyl Alcohol SCHEMBL9753897 | 0.75 | ALDH1A1 (0.35) | GAAKDM4EALDH1A1HSD17B10NPSR1 | |
| SCHEMBL9753831 | 0.74 | GAA (0.31) | GAA | |
| SCHEMBL8608929 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0436831-A2 | Imidazo[1,2-a]pyridinylalkyl compounds for treatment of neurotoxic injury | G.D. Searle & Co. (US) | 1991-07-17 | — | — | EP | claimed |
| WO-1991008211-A1 | IMIDAZO[1,2-a]PYRIDINYLALKYL COMPOUNDS FOR TREATMENT OF NEUROTOXIC INJURY | G.D. SEARLE & CO. (US) | 1991-06-13 | — | — | WO | claimed |
| EP-0436831-A2 | Imidazo[1,2-a]pyridinylalkyl compounds for treatment of neurotoxic injury | G.D. Searle & Co. (US) | 1991-07-17 | — | — | EP | disclosed |
| WO-1991008211-A1 | IMIDAZO[1,2-a]PYRIDINYLALKYL COMPOUNDS FOR TREATMENT OF NEUROTOXIC INJURY | G.D. SEARLE & CO. (US) | 1991-06-13 | — | — | WO | disclosed |