Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 1/20 | 0.51 |
| ▸ | PGK2 | P07205 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ACP3 | P15309 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9753705 | 0.77 | FBP1 (0.34) | PGK1PGK2NPC1GAAKDM4E | |
| SCHEMBL8606782 | 0.73 | PTGS1 (0.49) | RAB9ATP53MAPTNPC1GAA | |
| SCHEMBL8606880 | 0.71 | PGK1 (0.42) | PGK1PGK2ACP3SMN1; SMN2GAA | |
| SCHEMBL8607760 | 0.66 | PTGS1 (0.44) | PGK1PGK2RAB9ATP53ACP3 | |
| SCHEMBL8606805 | 0.65 | PGK1 (0.39) | PGK1PGK2ACP3SMN1; SMN2 | |
| SCHEMBL103693 | 0.64 | MAPT (0.55) | RAB9ATP53SMN1; SMN2MAPTMEN1 | |
| SCHEMBL10515790 | 0.62 | RAB9A (0.54) | RAB9ATP53SMN1; SMN2MAPTMEN1 | |
| SCHEMBL4542167 | 0.62 | PGK1 (0.74) | PGK1PGK2ACP3SMN1; SMN2 | |
| SCHEMBL9753684 | 0.61 | GGPS1 (0.35) | — | |
| SCHEMBL8608520 | 0.61 | PGK1 (0.32) | PGK1PGK2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991008211-A1 | IMIDAZO[1,2-a]PYRIDINYLALKYL COMPOUNDS FOR TREATMENT OF NEUROTOXIC INJURY | G.D. SEARLE & CO. (US) | 1991-06-13 | — | — | WO | disclosed |