Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MITF | O75030 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8657646 | 0.80 | ALDH1A1 (0.47) | ALDH1A1MAPK1MAPTMEN1KMT2A | |
| SCHEMBL27717189 | 0.72 | MAPT (0.48) | ALDH1A1MAPK1MAPTMEN1KMT2A | |
| SCHEMBL17937195 | 0.71 | ALDH1A1 (0.55) | ALDH1A1MAPK1L3MBTL1MAPTMEN1 | |
| SCHEMBL2343365 | 0.71 | ALDH1A1 (0.51) | ALDH1A1MAPK1L3MBTL1MAPTMEN1 | |
| SCHEMBL3818181 | 0.71 | ALDH1A1 (0.67) | ALDH1A1MAPK1L3MBTL1MAPTMEN1 | |
| SCHEMBL20126457 | 0.71 | ALDH1A1 (0.58) | ALDH1A1MAPK1L3MBTL1MAPTMEN1 | |
| SCHEMBL27752573 | 0.70 | CYP3A4 (0.49) | ALDH1A1MAPK1MAPTMEN1KMT2A | |
| SCHEMBL3929230 | 0.70 | L3MBTL1 (0.44) | ALDH1A1MAPK1L3MBTL1MAPTMEN1 | |
| SCHEMBL6310812 | 0.68 | ALDH1A1 (0.63) | ALDH1A1MAPK1L3MBTL1MAPTMEN1 | |
| SCHEMBL3295395 | 0.68 | MGMT (0.51) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991009598-A1 | AZAOXINDOLE DERIVATIVES | PFIZER INC. (US) | 1991-07-11 | — | — | WO | disclosed |