Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1222497 | 0.83 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AMITFMAPK1 | |
| SCHEMBL9753801 | 0.80 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AMITFHPGD | |
| SCHEMBL574019 | 0.80 | MAPK1 (0.64) | ALDH1A1MEN1KMT2AHPGDMAPK1 | |
| SCHEMBL573796 | 0.80 | MAPT (0.44) | ALDH1A1MEN1KMT2AMITFHPGD | |
| SCHEMBL573797 | 0.80 | MAPT (0.44) | ALDH1A1MEN1KMT2AMITFHPGD | |
| SCHEMBL12884492 | 0.75 | PIN1 (0.39) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL3595491 | 0.72 | ITGA4 (0.42) | ALDH1A1MEN1KMT2AMITFMAPK1 | |
| SCHEMBL27717189 | 0.72 | MAPT (0.48) | ALDH1A1MEN1KMT2AMITFHPGD | |
| SCHEMBL18299041 | 0.71 | MAPK1 (0.41) | ALDH1A1MEN1KMT2AMITFHPGD | |
| SCHEMBL13617481 | 0.70 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2AMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811432-A | Azaoxindole derivatives | PFIZER INC (US) | 1998-09-22 | — | — | US | disclosed |
| WO-1991009598-A1 | AZAOXINDOLE DERIVATIVES | PFIZER INC. (US) | 1991-07-11 | — | — | WO | disclosed |
| EP-0436333-A2 | Azaoxindole derivatives | PFIZER INC. (US) | 1991-07-10 | — | — | EP | disclosed |