Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | PTGES | O14684 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9753948 | 1.00 | KDM4E (0.59) | KDM4ELMNAHPGDALDH1A1L3MBTL1 | |
| SCHEMBL9212578 | 0.91 | KDM4E (0.62) | KDM4ELMNAHPGDALDH1A1L3MBTL1 | |
| SCHEMBL9214196 | 0.91 | KDM4E (0.62) | KDM4ELMNAHPGDALDH1A1L3MBTL1 | |
| SCHEMBL9212595 | 0.91 | KDM4E (0.62) | KDM4ELMNAHPGDALDH1A1L3MBTL1 | |
| SCHEMBL4266835 | 0.82 | ALDH1A1 (0.61) | KDM4ELMNAHPGDALDH1A1L3MBTL1 | |
| SCHEMBL9663829 | 0.80 | PTGS1 (0.75) | KDM4ELMNAHPGDALDH1A1L3MBTL1 | |
| SCHEMBL9215071 | 0.80 | KDM4E (0.68) | KDM4ELMNAHPGDALDH1A1L3MBTL1 | |
| SCHEMBL9213622 | 0.79 | KDM4E (0.48) | KDM4ELMNAHPGDALDH1A1L3MBTL1 | |
| SCHEMBL9213632 | 0.79 | KDM4E (0.48) | KDM4ELMNAHPGDALDH1A1L3MBTL1 | |
| SCHEMBL18106939 | 0.78 | KDM4E (0.64) | KDM4ELMNAHPGDALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991009021-A1 | IMIDAZOLES | RHONE-POULENC SANTE (FR) | 1991-06-27 | — | — | WO | disclosed |