Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 7/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ACE | P12821 | 1/20 | 0.50 |
| ▸ | CMA1 | P23946 | 6/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9754021 | 1.00 | REN (0.62) | RENPOLBKMT2AACECMA1 | |
| SCHEMBL9754222 | 0.91 | REN (0.54) | RENPOLBKMT2AACEMEN1 | |
| SCHEMBL9754227 | 0.91 | REN (0.54) | RENPOLBKMT2AACEMEN1 | |
| SCHEMBL28067688 | 0.89 | ACE (0.56) | RENKMT2AACECMA1ATM | |
| SCHEMBL28067687 | 0.89 | ACE (0.56) | RENKMT2AACECMA1ATM | |
| SCHEMBL30279327 | 0.87 | REN (0.54) | RENPOLBKMT2AACECMA1 | |
| SCHEMBL30279311 | 0.84 | POLB (0.54) | RENPOLBKMT2AMEN1 | |
| SCHEMBL30689119 | 0.82 | CTRB1 (0.56) | RENKMT2AACECMA1MEN1 | |
| SCHEMBL13123112 | 0.82 | POLB (0.56) | POLBKMT2ACMA1L3MBTL1MEN1 | |
| SCHEMBL28379593 | 0.82 | POLB (0.66) | RENPOLBKMT2AL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991008221-A1 | PEPTIDE INHIBITORS OF HIV PROTEASE | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1991-06-13 | — | — | WO | disclosed |