Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 8/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9754222 | 1.00 | REN (0.54) | RENPOLBKMT2AMEN1HDAC3 | |
| SCHEMBL9754023 | 0.91 | REN (0.62) | RENPOLBKMT2AMEN1ACE | |
| SCHEMBL9754021 | 0.91 | REN (0.62) | RENPOLBKMT2AMEN1ACE | |
| SCHEMBL9754315 | 0.81 | CTSS (0.57) | RENKMT2AHDAC1HDAC6TACR1 | |
| SCHEMBL9754319 | 0.81 | CTSS (0.57) | RENKMT2AHDAC1HDAC6TACR1 | |
| SCHEMBL30279311 | 0.80 | POLB (0.54) | RENPOLBKMT2AMEN1HDAC3 | |
| SCHEMBL28067687 | 0.80 | ACE (0.56) | RENKMT2AMEN1ACEYAP1 | |
| SCHEMBL28067688 | 0.80 | ACE (0.56) | RENKMT2AMEN1ACEYAP1 | |
| SCHEMBL30279327 | 0.79 | REN (0.54) | RENPOLBKMT2AACE | |
| SCHEMBL28379593 | 0.78 | POLB (0.66) | RENPOLBKMT2AMEN1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991008221-A1 | PEPTIDE INHIBITORS OF HIV PROTEASE | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1991-06-13 | — | — | WO | disclosed |