Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 7/20 | 0.37 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27370123 | 0.86 | GRM5 (0.41) | SMN1; SMN2RAB9ANPC1GRM5MAPK8 | |
| SCHEMBL9854156 | 0.82 | SMN1; SMN2 (0.40) | SMN1; SMN2TDP1RAB9ANPC1GRM5 | |
| SCHEMBL9821199 | 0.74 | CHRNB2 (0.39) | NPC1KMT2AALDH1A1 | |
| SCHEMBL1721734 | 0.73 | MAPK8 (0.45) | SMN1; SMN2MAPK8KMT2AALDH1A1GAA | |
| SCHEMBL9854170 | 0.73 | KMT2A (0.36) | TDP1GRM5MAPK8KMT2APOLB | |
| SCHEMBL10523995 | 0.71 | MAPK8 (0.43) | SMN1; SMN2TDP1RAB9ANPC1MAPK8 | |
| SCHEMBL9854169 | 0.68 | HTT (0.34) | SMN1; SMN2TDP1GAA | |
| SCHEMBL10200326 | 0.67 | KDM4E (0.46) | MAPK8KMT2AALDH1A1GAAMAPT | |
| SCHEMBL17620147 | 0.66 | TRPA1 (0.40) | SMN1; SMN2TDP1RAB9ANPC1KMT2A | |
| SCHEMBL3056162 | 0.66 | SCN9A (0.50) | MAPK8POLBALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3184960-A | — | — | None | — | — | JP | disclosed |
| JP-H03184960-A | N-PYRIDYLAMIDE COMPOUND, ITS PRODUCTION AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE CONTAINING THE SANE | ISHIHARA SANGYO KAISHA LTD | 1991-08-12 | — | — | JP | disclosed |