Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 7/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 6/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17609879 | 0.85 | ALDH1A1 (0.40) | TRPA1RAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL31435328 | 0.74 | LMNA (0.39) | TRPA1RAB9ANPC1ALDH1A1MAPK1 | |
| SCHEMBL24427690 | 0.74 | LMNA (0.39) | TRPA1RAB9ANPC1ALDH1A1MAPK1 | |
| SCHEMBL21861632 | 0.71 | ALDH1A1 (0.40) | RAB9ANPC1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL21724410 | 0.68 | JAK2 (0.40) | RAB9ATDP1NPC1ALDH1A1TSHR | |
| SCHEMBL9754090 | 0.66 | SMN1; SMN2 (0.39) | RAB9ATDP1NPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL31104116 | 0.65 | NPSR1 (0.53) | RAB9ANPC1ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL19715634 | 0.64 | ENPP1 (0.41) | TSHR | |
| SCHEMBL29411821 | 0.64 | ENPP1 (0.41) | TSHR | |
| SCHEMBL25037163 | 0.63 | TDP1 (0.36) | RAB9ATDP1ALDH1A1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016044792-A1 | INHIBITING THE TRANSIENT RECEPTOR POTENTIAL A1 ION CHANNEL | HYDRA BIOSCIENCES, INC. (US) | 2016-03-24 | — | — | WO | disclosed |