Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL979295 | 0.82 | SIGMAR1 (1.00) | SIGMAR1KDM4EALDH1A1CASP6EPHX2 | |
| SCHEMBL1554811 | 0.81 | SIGMAR1 (0.48) | SIGMAR1KDM4EALDH1A1CASP6EPHX2 | |
| SCHEMBL983313 | 0.81 | SIGMAR1 (0.78) | SIGMAR1KDM4ECASP6EPHX2TDP1 | |
| SCHEMBL974452 | 0.70 | SIGMAR1 (0.66) | SIGMAR1ALDH1A1TSHR | |
| SCHEMBL974058 | 0.69 | SIGMAR1 (1.00) | SIGMAR1KDM4EEPHX2EPHX1 | |
| SCHEMBL5197128 | 0.69 | EPHX1 (0.56) | SIGMAR1KDM4EALDH1A1MAPTEPHX2 | |
| SCHEMBL10308298 | 0.68 | EPHX1 (0.59) | SIGMAR1KDM4EALDH1A1MAPTEPHX2 | |
| SCHEMBL19696814 | 0.68 | EPHX1 (0.59) | SIGMAR1KDM4EALDH1A1MAPTEPHX2 | |
| SCHEMBL1555360 | 0.68 | SIGMAR1 (0.52) | SIGMAR1KDM4ECASP6EPHX2EPHX1 | |
| SCHEMBL12573061 | 0.66 | EPHX1 (0.53) | SIGMAR1KDM4EALDH1A1MAPTEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011000945-A9 | AMINOALKAMIDES FOR USE IN THE TREATMENT OF INFLAMMATORY, DEGENERATIVE OR DEMYELINATING DISEASES OF THE CNS | NENSIUS RESEARCH A/S (DK) | 2011-04-07 | — | — | WO | claimed |
| WO-2011000945-A2 | AMINOALKAMIDES FOR USE IN THE TREATMENT OF INFLAMMATORY, DEGENERATIVE OR DEMYELINATING DISEASES OF THE CNS | NENSIUS RESEARCH A/S (DK) | 2011-01-06 | — | — | WO | claimed |
| WO-2011000945-A9 | AMINOALKAMIDES FOR USE IN THE TREATMENT OF INFLAMMATORY, DEGENERATIVE OR DEMYELINATING DISEASES OF THE CNS | NENSIUS RESEARCH A/S (DK) | 2011-04-07 | — | — | WO | disclosed |
| WO-2011000945-A2 | AMINOALKAMIDES FOR USE IN THE TREATMENT OF INFLAMMATORY, DEGENERATIVE OR DEMYELINATING DISEASES OF THE CNS | NENSIUS RESEARCH A/S (DK) | 2011-01-06 | — | — | WO | disclosed |