Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.78 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL974058 | 0.88 | SIGMAR1 (1.00) | SIGMAR1CHRM5CHRM3KDM4EEPHX1 | |
| SCHEMBL979295 | 0.82 | SIGMAR1 (1.00) | SIGMAR1CHRM5CHRM3KDM4EEPHX1 | |
| SCHEMBL11071000 | 0.81 | KDM4E (0.65) | SIGMAR1CHRM5CHRM3KDM4EEPHX1 | |
| SCHEMBL975435 | 0.81 | SIGMAR1 (0.70) | SIGMAR1KDM4EEPHX1EPHX2CASP6 | |
| SCHEMBL977989 | 0.76 | KDM4E (0.58) | SIGMAR1CHRM5CHRM3KDM4EEPHX1 | |
| SCHEMBL1021506 | 0.75 | KDM4E (0.58) | SIGMAR1CHRM5CHRM3KDM4EEPHX1 | |
| SCHEMBL27667325 | 0.72 | SIGMAR1 (0.44) | SIGMAR1CHRM5CHRM3OPRM1OPRD1 | |
| SCHEMBL1899938 | 0.72 | KDM4E (0.54) | SIGMAR1CHRM5CHRM3KDM4EEPHX1 | |
| SCHEMBL28716337 | 0.72 | LMNA (0.45) | SIGMAR1CHRM5CHRM3OPRM1OPRD1 | |
| SCHEMBL5197128 | 0.71 | EPHX1 (0.56) | SIGMAR1KDM4EEPHX1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011000945-A9 | AMINOALKAMIDES FOR USE IN THE TREATMENT OF INFLAMMATORY, DEGENERATIVE OR DEMYELINATING DISEASES OF THE CNS | NENSIUS RESEARCH A/S (DK) | 2011-04-07 | — | — | WO | claimed |
| WO-2011000945-A9 | AMINOALKAMIDES FOR USE IN THE TREATMENT OF INFLAMMATORY, DEGENERATIVE OR DEMYELINATING DISEASES OF THE CNS | NENSIUS RESEARCH A/S (DK) | 2011-04-07 | — | — | WO | disclosed |
| WO-2011000945-A2 | AMINOALKAMIDES FOR USE IN THE TREATMENT OF INFLAMMATORY, DEGENERATIVE OR DEMYELINATING DISEASES OF THE CNS | NENSIUS RESEARCH A/S (DK) | 2011-01-06 | — | — | WO | disclosed |