SCHEMBL9754422

SCHEMBL9754422

O=C(O)c1c(O)cccc1-c1ccc([N+](=O)[O-])cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
CA12 O43570 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
CA14 Q9ULX7 1/20 0.48
POLB P06746 1/20 0.47
MAPK1 P28482 1/20 0.47
TDP1 Q9NUW8 2/20 0.47
AR P10275 2/20 0.44
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44
SRD5A2 P31213 1/20 0.44
IKBKB O14920 1/20 0.43
MYC P01106 1/20 0.43
MAX P61244 1/20 0.43
TP53 P04637 1/20 0.42
NPC1 O15118 1/20 0.42
APP P05067 1/20 0.42
TNKS O95271 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL28595300 0.82 POLB (0.56) POLBMAPK1TDP1CES2CES1
SCHEMBL1539358 0.80 IKBKB (0.56) CA1CA2CA12CA9CA14
SCHEMBL3264678 0.79 CA12 (0.64) CA1CA2CA12CA7CA9
SCHEMBL9754581 0.79 PRKCZ (0.60) CA1CA2CA12CA7CA9
SCHEMBL2167279 0.79 POLB (0.42) POLBMAPK1TDP1ARCES2
SCHEMBL28239062 0.78 IKBKB (0.54) CA1CA2CA12CA9CA14
SCHEMBL22230412 0.78 HNF4A (0.65) POLBMAPK1TDP1CES2CES1
SCHEMBL7741933 0.77 MEN1 (0.49) POLBMAPK1TDP1ARCES2
SCHEMBL10046425 0.77 CA12 (0.80) CA1CA2CA12CA7CA9
SCHEMBL9754382 0.77 CA1 (0.55) CA1CA2CA12CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1991013065-A1 6-ARYL-2-SUBSTITUTED BENZOIC ACID HERBICIDES FMC CORPORATION (US) 1991-09-05 WO disclosed