Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.49 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.49 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.49 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9754405 | 0.87 | GRIN2D (0.53) | MAPTMAOBGRIN2DGRIN3BGRIN1 | |
| SCHEMBL31682616 | 0.87 | GRIN2D (0.53) | MAPTMAOBGRIN2DGRIN3BGRIN1 | |
| SCHEMBL5178571 | 0.87 | GRIN2D (0.53) | MAPTMAOBGRIN2DGRIN3BGRIN1 | |
| SCHEMBL20871094 | 0.86 | MAOB (0.56) | MAPTMAOBGRIN2DGRIN3BGRIN1 | |
| SCHEMBL3082834 | 0.85 | MAOB (0.51) | MAPTMAOBGRIN2DGRIN3BGRIN1 | |
| SCHEMBL19490683 | 0.85 | PTGS2 (0.48) | MAPTMAOBPTGS2ALDH1A1MEN1 | |
| SCHEMBL5179901 | 0.82 | NFE2L2 (0.65) | MAPTMAOBPTGS2GRIN2DGRIN3B | |
| SCHEMBL19624623 | 0.81 | SMN1; SMN2 (0.52) | MAPTMAOBGRIN2DGRIN3BGRIN1 | |
| SCHEMBL12416826 | 0.79 | CA2 (0.72) | PTGS2 | |
| SCHEMBL11510186 | 0.78 | PTGS2 (0.54) | MAPTMAOBPTGS2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214348-A2 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2021-10-28 | — | — | WO | disclosed |
| WO-2021074106-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2021-04-22 | — | — | WO | disclosed |