Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 17/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4431905 | 0.87 | KDM4E (0.69) | PTGER3ALDH1A1CYP1A2HPGDHSD17B10 | |
| SCHEMBL4433382 | 0.85 | ALDH1A1 (0.67) | PTGER3ALDH1A1CYP1A2HPGDHSD17B10 | |
| SCHEMBL9535126 | 0.84 | PTGER3 (0.54) | PTGER3ALDH1A1CYP1A2HPGDHSD17B10 | |
| SCHEMBL9539842 | 0.75 | KDM4E (0.42) | ALDH1A1CYP1A2HPGDHSD17B10KDM4E | |
| SCHEMBL9534054 | 0.74 | PTGER3 (0.53) | PTGER3ALDH1A1CYP1A2HPGDHSD17B10 | |
| SCHEMBL9536452 | 0.74 | PTGER3 (0.72) | PTGER3ALDH1A1CYP1A2HPGDHSD17B10 | |
| SCHEMBL9535753 | 0.73 | PTGER3 (0.50) | PTGER3ALDH1A1CYP1A2HPGDHSD17B10 | |
| SCHEMBL9535021 | 0.73 | GSK3B (0.47) | ALDH1A1HPGDKDM4EGAA | |
| SCHEMBL9536067 | 0.73 | PTGER3 (0.50) | PTGER3ALDH1A1CYP1A2HPGDHSD17B10 | |
| SCHEMBL9533551 | 0.73 | PTGER3 (0.50) | PTGER3ALDH1A1CYP1A2HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991017987-A1 | PHENOL AND PYRIDINOL DERIVATIVES AS PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1991-11-28 | — | — | WO | disclosed |