Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 15/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4431905 | 0.78 | KDM4E (0.69) | PTGER3ALDH1A1CYP1A2HPGDHSD17B10 | |
| SCHEMBL9534817 | 0.77 | TDP1 (0.45) | ALDH1A1CYP1A2HPGDHSD17B10KDM4E | |
| SCHEMBL9535126 | 0.76 | PTGER3 (0.54) | PTGER3ALDH1A1CYP1A2HPGDHSD17B10 | |
| SCHEMBL9538652 | 0.75 | TDP1 (0.54) | ALDH1A1CYP1A2HPGDHSD17B10KDM4E | |
| SCHEMBL9754352 | 0.74 | PTGER3 (0.48) | PTGER3ALDH1A1CYP1A2HPGDHSD17B10 | |
| SCHEMBL9754413 | 0.74 | PTGER3 (0.56) | PTGER3ALDH1A1CYP1A2HPGDHSD17B10 | |
| SCHEMBL14873474 | 0.74 | CCNC (0.52) | ALDH1A1MTORKDM4E | |
| SCHEMBL9537802 | 0.74 | PTGER3 (0.62) | PTGER3ALDH1A1CYP1A2HPGDHSD17B10 | |
| SCHEMBL28849409 | 0.73 | PTGER1 (0.51) | PTGER3MTOR | |
| SCHEMBL7363438 | 0.73 | RXRA (0.43) | ALDH1A1HPGDHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532531-A1 | PHENOL AND PYRIDINOL DERIVATIVES AS PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-03-24 | — | — | EP | claimed |
| WO-1991017987-A1 | PHENOL AND PYRIDINOL DERIVATIVES AS PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1991-11-28 | — | — | WO | claimed |
| EP-0532531-A1 | PHENOL AND PYRIDINOL DERIVATIVES AS PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-03-24 | — | — | EP | disclosed |
| WO-1991017987-A1 | PHENOL AND PYRIDINOL DERIVATIVES AS PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1991-11-28 | — | — | WO | disclosed |