Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.38 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9534117 | 0.84 | ALDH1A1 (0.45) | KDM4EBTKALDH1A1HSD17B10HPGD | |
| SCHEMBL16189453 | 0.79 | KDR (0.40) | ALDH1A1HSD17B10HPGDMAPK1CYP11B1 | |
| SCHEMBL3155981 | 0.77 | BTK (0.61) | KDM4EBTKALDH1A1HPGDKDR | |
| SCHEMBL16189114 | 0.77 | ACACA (0.41) | KDM4EALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL10304963 | 0.75 | PDE2A (0.48) | BTKALDH1A1HIF1AHSD17B10TSHR | |
| SCHEMBL16225055 | 0.74 | TGFBR1 (0.51) | KDM4EBTKALDH1A1HSD17B10TSHR | |
| SCHEMBL21083344 | 0.74 | TGFBR1 (0.48) | KDM4EBTKTSHRKDRTGFBR1 | |
| SCHEMBL27479812 | 0.74 | BTK (0.44) | BTKALDH1A1HSD17B10MAPK1KDR | |
| SCHEMBL14184254 | 0.74 | CYP11B1 (0.47) | KDM4EALDH1A1HIF1AHSD17B10HPGD | |
| SCHEMBL9535531 | 0.72 | RAC1 (0.49) | KDM4EBTKALDH1A1HPGDKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991017987-A1 | PHENOL AND PYRIDINOL DERIVATIVES AS PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1991-11-28 | — | — | WO | disclosed |