Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9423360 | 0.95 | CYP19A1 (0.55) | CYP19A1HPGDLMNASMN1; SMN2CCR2 | |
| SCHEMBL9396355 | 0.84 | CCR2 (0.55) | CYP19A1HPGDLMNASMN1; SMN2CCR2 | |
| SCHEMBL9423618 | 0.78 | CYP19A1 (0.46) | CYP19A1HPGDLMNASMN1; SMN2KDM4E | |
| SCHEMBL13531041 | 0.74 | CCR2 (0.55) | HPGDLMNASMN1; SMN2CCR2KDM4E | |
| SCHEMBL9423386 | 0.73 | CYP19A1 (0.44) | CYP19A1HPGDLMNACCR2KDM4E | |
| SCHEMBL9423456 | 0.71 | MAT2A (0.44) | CYP19A1CCR2 | |
| SCHEMBL2917482 | 0.70 | CYP19A1 (1.00) | CYP19A1LMNASMN1; SMN2HDAC1HDAC6 | |
| Hydrochloric Acid SCHEMBL9382670 | 0.69 | CYP19A1 (0.96) | CYP19A1LMNASMN1; SMN2HDAC1HDAC6 | |
| SCHEMBL29200758 | 0.68 | HPGD (0.60) | HPGDLMNASMN1; SMN2CCR2KDM4E | |
| SCHEMBL30783420 | 0.68 | HPGD (0.60) | HPGDLMNASMN1; SMN2CCR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991007401-A1 | 3-SUBSTITUTED-1-(ARYL OR ARYLALKYL)-2(1H)-QUINOLINONES | SCHERING CORPORATION (US) | 1991-05-30 | — | — | WO | disclosed |