Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.47 |
| ▸ | PPARA | Q07869 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 7/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PTPRF | P10586 | 2/20 | 0.39 |
| ▸ | PTPRA | P18433 | 2/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | PTPRB | P23467 | 1/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.39 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11713689 | 0.86 | ADRB2 (0.42) | PPARGPPARAMAPTPTPN1ADRB2 | |
| SCHEMBL7959198 | 0.80 | CYP2A6 (0.58) | PPARGPPARAMAPTPTPN1SMN1; SMN2 | |
| SCHEMBL8821208 | 0.79 | PPARG (0.67) | PPARGPPARASMN1; SMN2 | |
| SCHEMBL8935882 | 0.79 | PPARG (0.67) | PPARGPPARASMN1; SMN2 | |
| SCHEMBL1732896 | 0.77 | ADRB2 (0.46) | PPARGPPARAMAPTADRB2SMN1; SMN2 | |
| SCHEMBL10431486 | 0.77 | ADRB2 (0.45) | MAPTADRB2MAOASMN1; SMN2CYP2C9 | |
| SCHEMBL6601225 | 0.76 | ADRB2 (0.47) | ADRB2MAOASMN1; SMN2 | |
| SCHEMBL1926672 | 0.76 | MAOA (0.47) | MAPTADRB2MAOAAPEX1SMN1; SMN2 | |
| SCHEMBL9648991 | 0.75 | MAOA (0.59) | PPARGPPARAMAPTMAOASMN1; SMN2 | |
| SCHEMBL22730026 | 0.74 | PPARG (0.49) | PPARGPPARAMAPTPTPN1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991014688-A1 | HETERO POLYCYCLIC BIOCIDAL COMPOUNDS AND THEIR USE IN MEDECINE | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-10-03 | — | — | WO | disclosed |
| EP-0447703-A1 | Hetero polycyclic biocidal compounds, their synthesis and intermediates therefor,formulations containing them and their use in medicine | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-09-25 | — | — | EP | disclosed |