Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.47 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.47 |
| ▸ | CSNK2A3 | Q8NEV1 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 4/20 | 0.41 |
| ▸ | TTR | P02766 | 2/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9754603 | 0.83 | ALDH1A1 (0.45) | KDM4EGLAMAPTTSHRHSD17B10 | |
| SCHEMBL9754506 | 0.79 | CSNK2A1 (0.49) | CSNK2A1KDM4ECSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL9778972 | 0.76 | KDM4E (0.45) | KDM4EHPGDGLAMAPTHSD17B10 | |
| SCHEMBL9843531 | 0.76 | MGAM (0.41) | KDM4EHPGDGLAMAPTHSD17B10 | |
| SCHEMBL9754508 | 0.71 | KDM4E (0.52) | CSNK2A1KDM4ECSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL9754456 | 0.71 | PIM1 (0.63) | CSNK2A1KDM4ECSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL9102343 | 0.68 | ERN1 (0.51) | KDM4EHPGDGLAMAPTHSD17B10 | |
| SCHEMBL2895883 | 0.67 | HPGD (0.64) | CSNK2A1KDM4ECSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL11372717 | 0.67 | KDM4E (0.47) | CSNK2A1KDM4ECSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL11591196 | 0.66 | GAA (0.56) | CSNK2A1KDM4ECSNK2A2CSNK2BCSNK2A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991014688-A1 | HETERO POLYCYCLIC BIOCIDAL COMPOUNDS AND THEIR USE IN MEDECINE | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-10-03 | — | — | WO | disclosed |
| EP-0447703-A1 | Hetero polycyclic biocidal compounds, their synthesis and intermediates therefor,formulations containing them and their use in medicine | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-09-25 | — | — | EP | disclosed |