Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.50 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.50 |
| ▸ | GPR3 | P46089 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13564071 | 0.82 | GPR3 (0.71) | ALKBH5FTOGPR3HSP90AA1IDO1 | |
| SCHEMBL3423943 | 0.78 | GPR3 (0.71) | ALKBH5FTOGPR3HSP90AA1IDO1 | |
| SCHEMBL20426454 | 0.78 | KDM4E (0.47) | ALKBH5FTOHSP90AA1IDO1KDM4E | |
| SCHEMBL20426444 | 0.78 | L3MBTL1 (0.52) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL20427323 | 0.74 | KDM4E (0.36) | KDM4EL3MBTL1ATM | |
| SCHEMBL20402131 | 0.73 | ALKBH5 (0.50) | ALKBH5FTOGPR3HSP90AA1IDO1 | |
| SCHEMBL9754648 | 0.73 | GPR3 (0.44) | ALKBH5FTOGPR3HSP90AA1IDO1 | |
| SCHEMBL20426468 | 0.73 | L3MBTL1 (0.42) | KDM4EMAPTALDH1A1MEN1HTT | |
| SCHEMBL257568 | 0.73 | ALKBH5 (0.58) | ALKBH5FTOGPR3HSP90AA1IDO1 | |
| SCHEMBL8503438 | 0.73 | GPR3 (0.58) | ALKBH5FTOGPR3HSP90AA1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991014688-A1 | HETERO POLYCYCLIC BIOCIDAL COMPOUNDS AND THEIR USE IN MEDECINE | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-10-03 | — | — | WO | disclosed |
| EP-0447703-A1 | Hetero polycyclic biocidal compounds, their synthesis and intermediates therefor,formulations containing them and their use in medicine | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-09-25 | — | — | EP | disclosed |