Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | AHR | P35869 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9754656 | 0.99 | LMNA (0.37) | LMNANPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL9843623 | 0.81 | ADRB2 (0.39) | LMNANPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL9524760 | 0.81 | KDM4E (0.46) | NPC1RAB9AALDH1A1MAPTSLC2A1 | |
| Hydrochloric Acid SCHEMBL9754528 | 0.80 | ADRB2 (0.38) | LMNANPC1RAB9ASMN1; SMN2CYP1A2 | |
| Hydrochloric Acid SCHEMBL9526162 | 0.80 | KDM4E (0.45) | NPC1RAB9AALDH1A1MAPTSLC2A1 | |
| SCHEMBL9779167 | 0.80 | SLC2A1 (0.41) | LMNANPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL9525920 | 0.78 | CYP1A2 (0.47) | LMNANPC1RAB9ASMN1; SMN2CYP1A2 | |
| Hydrochloric Acid SCHEMBL9526903 | 0.77 | CYP1A2 (0.46) | LMNANPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL9779113 | 0.76 | SLC2A1 (0.48) | LMNANPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL9526537 | 0.74 | SLC2A1 (0.40) | LMNACYP1A2CYP2C19ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991014688-A1 | HETERO POLYCYCLIC BIOCIDAL COMPOUNDS AND THEIR USE IN MEDECINE | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-10-03 | — | — | WO | claimed |
| EP-0447703-A1 | Hetero polycyclic biocidal compounds, their synthesis and intermediates therefor,formulations containing them and their use in medicine | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-09-25 | — | — | EP | claimed |
| WO-1991014688-A1 | HETERO POLYCYCLIC BIOCIDAL COMPOUNDS AND THEIR USE IN MEDECINE | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-10-03 | — | — | WO | disclosed |
| EP-0447703-A1 | Hetero polycyclic biocidal compounds, their synthesis and intermediates therefor,formulations containing them and their use in medicine | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-09-25 | — | — | EP | disclosed |