Ether

Ether

SCHEMBL9754657

CCOCC.Oc1ccccc1Br

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.41
HTT P42858 2/20 0.41
CA2 P00918 4/20 0.39
CA1 P00915 3/20 0.39
CA12 O43570 2/20 0.39
CA14 Q9ULX7 2/20 0.39
CA7 P43166 2/20 0.39
CA9 Q16790 1/20 0.39
TSHR P16473 3/20 0.38
KDM4E B2RXH2 3/20 0.38
LMNA P02545 3/20 0.38
IDO1 P14902 2/20 0.38
NPC1 O15118 2/20 0.38
ALDH1A1 P00352 2/20 0.38
RAB9A P51151 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
CA4 P22748 2/20 0.38
MAPT P10636 2/20 0.38
GMNN O75496 1/20 0.38
EGFR P00533 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propane SCHEMBL29021125 0.86 ALDH1A1 (0.45) HPGDCA2CA1CA12CA14
Catechol SCHEMBL5431374 0.84 CA2 (0.56) HPGDCA2CA1CA12CA14
Catechol SCHEMBL27085 0.84 CA2 (0.56) HPGDCA2CA1CA12CA14
Methoxymethane SCHEMBL632535 0.81 CA2 (0.48) HPGDCA2CA1CA12CA14
SCHEMBL3440828 0.81 ALDH1A1 (0.56) HPGDHTTCA2CA1CA12
SCHEMBL15059320 0.81
SCHEMBL49313 0.81
SCHEMBL29573828 0.81
Pentane SCHEMBL27873627 0.80 TSHR (0.42) HPGDHTTCA2CA12CA14
Catechol SCHEMBL9616729 0.79 CA2 (0.50) HPGDCA2CA1CA12CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2049756-A None JP disclosed
JP-3056451-A None JP disclosed
JP-H0356451-A NOVEL DIPHENYLAMINE DERIVATIVE AND PRODUCTION THEREOF MITSUI TOATSU CHEM INC 1991-03-12 JP disclosed
JP-H0249756-A PRODUCTION OF DIPHENYLAMINE DERIVATIVE MITSUI TOATSU CHEM INC 1990-02-20 JP disclosed