Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9754686 | 0.92 | ITGB3 (0.40) | LMNAL3MBTL1SMN1; SMN2MAPK1ITGB3 | |
| SCHEMBL6130186 | 0.89 | ITGB3 (0.41) | LMNAITGB3ITGA2BHRH3HDAC6 | |
| SCHEMBL3337469 | 0.86 | LMNA (0.39) | LMNAL3MBTL1SMN1; SMN2MAPK1HRH3 | |
| SCHEMBL17633568 | 0.85 | LMNA (0.39) | LMNAL3MBTL1SMN1; SMN2MAPK1HRH3 | |
| Hydrochloric Acid SCHEMBL3337935 | 0.85 | LMNA (0.39) | LMNAL3MBTL1SMN1; SMN2MAPK1HRH3 | |
| SCHEMBL6130195 | 0.85 | ITGB3 (0.45) | SMN1; SMN2ITGB3ITGA2BHDAC6HDAC1 | |
| SCHEMBL3916325 | 0.85 | ITGB3 (0.45) | SMN1; SMN2ITGB3ITGA2BHDAC6HDAC1 | |
| SCHEMBL8678436 | 0.85 | ITGB3 (0.45) | SMN1; SMN2ITGB3ITGA2BHDAC6HDAC1 | |
| SCHEMBL8678394 | 0.85 | ITGB3 (0.45) | SMN1; SMN2ITGB3ITGA2BHDAC6HDAC1 | |
| SCHEMBL3334899 | 0.82 | EPHX1 (0.42) | LMNASMN1; SMN2HRH3XDHNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992000068-A1 | SUBSTITUTED HISTIDINES | SMITHKLINE BEECHAM CORPORATION (US) | 1992-01-09 | — | — | WO | disclosed |