Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.36 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.34 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.34 |
| ▸ | CHRNG | P07510 | 2/20 | 0.34 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.34 |
| ▸ | CHRND | Q07001 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CPB1 | P15086 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3916325 | 0.96 | ITGB3 (0.45) | ITGB3ITGA2BHDAC6HDAC1NOD1 | |
| SCHEMBL8678394 | 0.96 | ITGB3 (0.45) | ITGB3ITGA2BHDAC6HDAC1NOD1 | |
| SCHEMBL6130195 | 0.96 | ITGB3 (0.45) | ITGB3ITGA2BHDAC6HDAC1NOD1 | |
| SCHEMBL8678436 | 0.96 | ITGB3 (0.45) | ITGB3ITGA2BHDAC6HDAC1NOD1 | |
| SCHEMBL9754686 | 0.92 | ITGB3 (0.40) | ITGB3ITGA2BHDAC6HDAC1NOD1 | |
| SCHEMBL8679276 | 0.90 | SLC6A5 (0.44) | ITGB3ITGA2BNOD1 | |
| SCHEMBL9754660 | 0.89 | LMNA (0.37) | ITGB3ITGA2BHDAC6HDAC1LMNA | |
| SCHEMBL6130220 | 0.89 | HDAC6 (0.39) | ITGB3ITGA2BHDAC6HDAC1LMNA | |
| SCHEMBL8676729 | 0.89 | SLC6A5 (0.43) | ITGB3ITGA2B | |
| SCHEMBL8677099 | 0.89 | SLC6A5 (0.43) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1328620-A4 | COMPOSITIONS AND METHODS FOR DELAYING, PREVENTING, REJUVENATING OR REVERSING SENESCENCE IN CELLS | BETA PEPTIDE FOUND PTY LTD (AU) | 2005-11-09 | — | — | EP | disclosed |
| US-20040014814-A1 | Compositions and methods for delaying preventing rejuvenating or reversing senescence in cells | BETA PEPTIDE FOUNDATION PTY LTD., THE (AU) | 2004-01-22 | — | — | US | disclosed |
| EP-1328620-A1 | COMPOSITIONS AND METHODS FOR DELAYING, PREVENTING, REJUVENATING OR REVERSING SENESCENCE IN CELLS | The Beta Peptide Foundation Pty Ltd (AU) | 2003-07-23 | — | — | EP | disclosed |
| WO-2002026940-A1 | COMPOSITIONS AND METHODS FOR DELAYING, PREVENTING, REJUVENATING OR REVERSING SENESCENCE IN CELLS | THE BETA PEPTIDE FOUNDATION PTY LTD (AU) | 2002-04-04 | — | — | WO | disclosed |