Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | GLA | P06280 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 9/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4951837 | 0.83 | ALDH1A1 (0.73) | MEN1KMT2AALDH1A1SMN1; SMN2GLA | |
| SCHEMBL8913032 | 0.79 | ABCG2 (0.70) | ABCG2MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL18549022 | 0.78 | ALDH1A1 (0.66) | MEN1KMT2AALDH1A1SMN1; SMN2GLA | |
| SCHEMBL14117517 | 0.78 | ALDH1A1 (0.66) | MEN1KMT2AALDH1A1SMN1; SMN2GLA | |
| SCHEMBL10654333 | 0.78 | ALDH1A1 (0.49) | ABCG2MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9003269 | 0.76 | MAPT (0.70) | MEN1KMT2AALDH1A1SMN1; SMN2GLA | |
| SCHEMBL8973131 | 0.75 | ABCG2 (0.74) | ABCG2MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL10685272 | 0.75 | ALDH1A1 (0.46) | ABCG2MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL13558679 | 0.74 | KMT2A (0.53) | KMT2AALDH1A1CA12CA1CA2 | |
| SCHEMBL9651956 | 0.73 | MAPT (0.68) | MEN1KMT2AALDH1A1SMN1; SMN2GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991013881-A1 | PARAPHENYLENEDIAMINE DERIVATIVES AND THEIR USE IN OXIDATIVE DYES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1991-09-19 | — | — | WO | disclosed |