Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 9/20 | 0.37 |
| ▸ | DRD2 | P14416 | 4/20 | 0.37 |
| ▸ | DRD3 | P35462 | 4/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | DAO | P14920 | 2/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL134748 | 1.00 | HTR3A (0.43) | HTR3AALDH1A1CYP1A2CYP2C19ADRB2 | |
| SCHEMBL134747 | 1.00 | HTR3A (0.43) | HTR3AALDH1A1CYP1A2CYP2C19ADRB2 | |
| SCHEMBL10830907 | 0.81 | HTR3A (0.47) | HTR3AADRB2HTR1ADRD2DRD3 | |
| SCHEMBL13703832 | 0.76 | HTR3A (0.39) | HTR3AALDH1A1ADRB2HTR1ADRD2 | |
| SCHEMBL7003840 | 0.76 | KDM4E (0.38) | HTR3AALDH1A1CYP1A2CYP2C19KDM4E | |
| SCHEMBL7003839 | 0.76 | KDM4E (0.38) | HTR3AALDH1A1CYP1A2CYP2C19KDM4E | |
| SCHEMBL97632 | 0.74 | HTR3A (0.48) | HTR3AADRB2HTR1ADRD2DRD3 | |
| SCHEMBL98086 | 0.72 | KDM4E (0.40) | HTR3AALDH1A1CYP1A2CYP2C19HTR1A | |
| SCHEMBL15840472 | 0.70 | HTR3A (0.51) | HTR3AADRB2HTR1ADRD2DRD3 | |
| SCHEMBL7160420 | 0.70 | PARP1 (0.52) | HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3190114-B1 | PROCESS FOR MAKING A CRYSTALLINE ZILPATEROL SALT | INTERVET INT BV (NL) | 2019-11-06 | — | — | EP | disclosed |
| EP-2935275-B9 | AN IMPROVED PROCESS FOR MAKING ZILPATEROL | INTERVET INT BV (NL) | 2017-10-11 | — | — | EP | disclosed |
| EP-3190114-A1 | PROCESS FOR MAKING A CRYSTALLINE ZILPATEROL SALT | Intervet International B.V. (NL) | 2017-07-12 | — | — | EP | disclosed |
| US-9630967-B2 | Process for making zilpaterol | INTERVET INC. (US) | 2017-04-25 | — | — | US | disclosed |
| US-9630967-B2 | Process for making zilpaterol | INTERVET INC. (US) | 2017-04-25 | — | — | US | disclosed |
| EP-2935275-B1 | AN IMPROVED PROCESS FOR MAKING ZILPATEROL | INTERVET INT BV (NL) | 2017-03-08 | — | — | EP | disclosed |
| EP-2535340-B1 | Process for making zilpaterol and salts thereof | INTERVET INT BV (NL) | 2016-04-27 | — | — | EP | disclosed |
| US-20150315195-A1 | AN IMPROVED PROCESS FOR MAKING ZILPATEROL | INTERVET INC. (US) | 2015-11-05 | — | — | US | disclosed |
| US-20150315195-A1 | AN IMPROVED PROCESS FOR MAKING ZILPATEROL | INTERVET INC. (US) | 2015-11-05 | — | — | US | disclosed |
| EP-2142553-B1 | PROCESSES FOR MAKING ZILPATEROL AND SALTS THEREOF | INTERVET INT BV (NL) | 2015-08-19 | — | — | EP | disclosed |
| US-8362006-B2 | Processes for making zilpaterol and salts thereof | INTERVET INTERNATIONAL B.V. (NL) | 2013-01-29 | — | — | US | disclosed |
| US-8343956-B2 | Process for making a crystalline zilpaterol salt | INTERVET INTERNATIONAL B.V. (NL) | 2013-01-01 | — | — | US | disclosed |
| US-8343956-B2 | Process for making a crystalline zilpaterol salt | INTERVET INTERNATIONAL B.V. (NL) | 2013-01-01 | — | — | US | disclosed |
| EP-2535340-A2 | Process for making zilpaterol and salts thereof | Intervet International B.V. (NL) | 2012-12-19 | — | — | EP | disclosed |
| US-20120058189-A1 | PROCESS FOR MAKING A CRYSTALLINE ZILPATEROL SALT | INTERVET INTERNATIONAL B.V. (NL) | 2012-03-08 | — | — | US | disclosed |
| US-20120058189-A1 | PROCESS FOR MAKING A CRYSTALLINE ZILPATEROL SALT | INTERVET INTERNATIONAL B.V. (NL) | 2012-03-08 | — | — | US | disclosed |
| WO-2010070004-A1 | PROCESS FOR MAKING A CRYSTALLINE ZILPATEROL SALT | INTERVET INTERNATIONAL B.V. (NL) | 2010-06-24 | — | — | WO | disclosed |
| US-20100121050-A1 | PROCESSES FOR MAKING ZILPATEROL AND SALTS THEREOF | INTERVET INTERNATIONAL B.V. (NL) | 2010-05-13 | — | — | US | disclosed |
| US-20100121050-A1 | PROCESSES FOR MAKING ZILPATEROL AND SALTS THEREOF | INTERVET INTERNATIONAL B.V. (NL) | 2010-05-13 | — | — | US | disclosed |
| WO-2008119754-A1 | PROCESSES FOR MAKING ZILPATEROL AND SALTS THEREOF | INTERVET INTERNATIONAL B.V. (NL) | 2008-10-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100121050-A1 | PROCESSES FOR MAKING ZILPATEROL AND SALTS THEREOF | SLC39A11, SLC39A3, ZFR | HTR3A 4366/4885ALDH1A1 2559/4885CYP1A2 656/4885 |
| US-20120058189-A1 | PROCESS FOR MAKING A CRYSTALLINE ZILPATEROL SALT | ZFX, SLC39A11, ZNF277 | HTR3A 4341/4885ALDH1A1 4450/4885CYP1A2 1679/4885 |
| US-20150315195-A1 | AN IMPROVED PROCESS FOR MAKING ZILPATEROL | PPIP5K2, PPIA, ITPA | HTR3A 4024/4885ALDH1A1 1754/4885CYP1A2 349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.