Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 14/20 | 0.43 |
| ▸ | DRD2 | P14416 | 5/20 | 0.43 |
| ▸ | DRD3 | P35462 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1405158 | 0.84 | HTR3A (0.50) | HTR3AADRB2OPRM1HTR1ADRD2 | |
| SCHEMBL14902344 | 0.84 | HTR3A (0.50) | HTR3AADRB2OPRM1HTR1ADRD2 | |
| SCHEMBL17220917 | 0.84 | HTR3A (0.50) | HTR3AADRB2OPRM1HTR1ADRD2 | |
| SCHEMBL14045443 | 0.84 | HTR3A (0.50) | HTR3AADRB2OPRM1HTR1ADRD2 | |
| SCHEMBL17236545 | 0.84 | HTR3A (0.50) | HTR3AADRB2OPRM1HTR1ADRD2 | |
| SCHEMBL17220894 | 0.84 | HTR3A (0.50) | HTR3AADRB2OPRM1HTR1ADRD2 | |
| SCHEMBL14194855 | 0.81 | HTR1A (0.48) | HTR3AADRB2OPRM1HTR1ADRD2 | |
| SCHEMBL15840469 | 0.78 | ADRB2 (0.58) | HTR3AADRB2OPRM1HTR1ADRD2 | |
| SCHEMBL97632 | 0.74 | HTR3A (0.48) | HTR3AADRB2OPRM1HTR1ADRD2 | |
| SCHEMBL7160420 | 0.73 | PARP1 (0.52) | HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2935275-B9 | AN IMPROVED PROCESS FOR MAKING ZILPATEROL | INTERVET INT BV (NL) | 2017-10-11 | — | — | EP | disclosed |
| EP-2935275-B9 | AN IMPROVED PROCESS FOR MAKING ZILPATEROL | INTERVET INT BV (NL) | 2017-10-11 | — | — | EP | disclosed |
| US-9630967-B2 | Process for making zilpaterol | INTERVET INC. (US) | 2017-04-25 | — | — | US | disclosed |
| US-9630967-B2 | Process for making zilpaterol | INTERVET INC. (US) | 2017-04-25 | — | — | US | disclosed |
| US-9630967-B2 | Process for making zilpaterol | INTERVET INC. (US) | 2017-04-25 | — | — | US | disclosed |
| EP-2935275-B1 | AN IMPROVED PROCESS FOR MAKING ZILPATEROL | INTERVET INT BV (NL) | 2017-03-08 | — | — | EP | disclosed |
| EP-2935275-B1 | AN IMPROVED PROCESS FOR MAKING ZILPATEROL | INTERVET INT BV (NL) | 2017-03-08 | — | — | EP | disclosed |
| US-20150315195-A1 | AN IMPROVED PROCESS FOR MAKING ZILPATEROL | INTERVET INC. (US) | 2015-11-05 | — | — | US | disclosed |
| US-20150315195-A1 | AN IMPROVED PROCESS FOR MAKING ZILPATEROL | INTERVET INC. (US) | 2015-11-05 | — | — | US | disclosed |
| US-20150315195-A1 | AN IMPROVED PROCESS FOR MAKING ZILPATEROL | INTERVET INC. (US) | 2015-11-05 | — | — | US | disclosed |
| US-20150094331-A1 | QUINOLONE INHIBITORS OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 | AUSPEX PHARMACEUTICALS, INC. (US) | 2015-04-02 | — | — | US | disclosed |
| WO-2014095822-A1 | AN IMPROVED PROCESS FOR MAKING ZILPATEROL | INTERVET INTERNATIONAL B.V. (NL) | 2014-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150094331-A1 | QUINOLONE INHIBITORS OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 | PLA2G12A, PLA2G4A, PLA2G2A | HTR3A 2145/4885ADRB2 983/4885OPRM1 4659/4885 |
| US-20150315195-A1 | AN IMPROVED PROCESS FOR MAKING ZILPATEROL | PPIP5K2, PPIA, ITPA | HTR3A 4024/4885ADRB2 2118/4885OPRM1 3610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.