Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17720780 | 0.86 | KDM4E (0.44) | KDM4EHPGDHSD17B10PTPN1EGFR | |
| SCHEMBL27489237 | 0.86 | BACE1 (0.51) | KDM4EHPGDHSD17B10CYP4F2CYP4A11 | |
| SCHEMBL6950322 | 0.83 | KDM4E (0.46) | KDM4EHPGDHSD17B10ALDH1A1LMNA | |
| SCHEMBL17720767 | 0.81 | EGFR (0.55) | KDM4EHPGDHSD17B10EGFRSMN1; SMN2 | |
| SCHEMBL7229895 | 0.81 | CYP1A1 (0.46) | KDM4EHPGDCYP4F2CYP4A11SMN1; SMN2 | |
| SCHEMBL534889 | 0.77 | KDM4E (0.50) | KDM4EHPGDHSD17B10CYP4F2CYP4A11 | |
| SCHEMBL1834873 | 0.77 | KDM4E (0.61) | KDM4EHPGDHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL8904461 | 0.75 | LMNA (0.43) | KDM4EHPGDCYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL27368090 | 0.75 | BACE1 (0.49) | KDM4EHPGDHSD17B10PTPN1CYP4F2 | |
| SCHEMBL17720805 | 0.75 | PDE4D (0.47) | KDM4EHPGDHSD17B10PTPN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991013063-A1 | NEW BENZIMIDAZOLE DERIVATIVES, METHOD FOR PREPARING THEM AND THEIR PHARMACEUTICAL USE | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1991-09-05 | — | — | WO | disclosed |