Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | FABP3 | P05413 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1834873 | 0.88 | KDM4E (0.61) | KDM4EHPGDHSD17B10LMNATDP1 | |
| SCHEMBL15555970 | 0.85 | SLC6A3 (0.56) | KDM4EHPGDHSD17B10LMNATDP1 | |
| SCHEMBL28530771 | 0.85 | SLC6A4 (0.58) | KDM4EHPGDHSD17B10LMNASLC6A4 | |
| SCHEMBL6254697 | 0.84 | KDM4E (0.63) | KDM4EHPGDHSD17B10LMNATDP1 | |
| SCHEMBL6447567 | 0.83 | LMNA (0.55) | KDM4ELMNATDP1MAPK1L3MBTL1 | |
| SCHEMBL709954 | 0.83 | LMNA (0.51) | KDM4ELMNATDP1MAPK1L3MBTL1 | |
| SCHEMBL867780 | 0.83 | MAOB (0.52) | KDM4EHPGDHSD17B10LMNATDP1 | |
| SCHEMBL6447472 | 0.83 | LMNA (0.46) | KDM4EHPGDLMNATDP1MAPK1 | |
| SCHEMBL17066644 | 0.82 | BCHE (0.49) | LMNAALDH1A1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL6950322 | 0.81 | KDM4E (0.46) | KDM4EHPGDHSD17B10LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991013063-A1 | NEW BENZIMIDAZOLE DERIVATIVES, METHOD FOR PREPARING THEM AND THEIR PHARMACEUTICAL USE | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1991-09-05 | — | — | WO | disclosed |