SCHEMBL867780

SCHEMBL867780

CC(=O)Oc1ccccc1-c1ccc(C)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.52
LMNA P02545 5/20 0.51
TDP1 Q9NUW8 2/20 0.51
MAPK1 P28482 2/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
TSHR P16473 3/20 0.49
KDM4E B2RXH2 3/20 0.49
ALDH1A1 P00352 3/20 0.49
HSD17B10 Q99714 2/20 0.49
PTGS2 P35354 2/20 0.49
ESR1 P03372 1/20 0.49
ITGB3 P05106 1/20 0.49
ITGA2B P08514 1/20 0.49
HMGB1 P09429 1/20 0.49
HPGD P15428 1/20 0.49
GGT1 P19440 1/20 0.49
PTGS1 P23219 1/20 0.49
BLM P54132 1/20 0.49
NAPRT Q6XQN6 1/20 0.49
BACE1 P56817 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3728321 0.87 KDM4E (0.58) LMNATDP1MAPK1L3MBTL1TSHR
SCHEMBL27849556 0.87 ADORA3 (0.55) MAOBLMNATDP1MAPK1L3MBTL1
SCHEMBL6447567 0.86 LMNA (0.55) LMNATDP1MAPK1L3MBTL1KDM4E
SCHEMBL709954 0.86 LMNA (0.51) MAOBLMNATDP1MAPK1L3MBTL1
SCHEMBL9788610 0.86 BACE1 (0.56) LMNATDP1MAPK1TSHRKDM4E
SCHEMBL10448930 0.86 PREP (0.53) LMNATDP1MAPK1TSHRKDM4E
SCHEMBL27559161 0.85 BACE1 (0.58) MAOBLMNATDP1MAPK1L3MBTL1
Bicarbonate SCHEMBL9330276 0.85 KDM4E (0.56) LMNATDP1MAPK1L3MBTL1TSHR
SCHEMBL16192590 0.85 LMNA (0.48) MAOBLMNATDP1MAPK1L3MBTL1
SCHEMBL10783055 0.84 SMN1; SMN2 (0.53) MAOBLMNATDP1MAPK1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108601958-B Pro-fragrance compositions 爱客多有限公司 2022-06-17 CN claimed
EP-2211829-B1 IMPROVEMENT OF THE FRAGRANCE EFFECT OF PERFUME ESTERS HENKEL AG & CO KGAA (DE) 2011-04-27 EP claimed
US-20100210496-A1 Fragrance Effect of Perfume Esters BESSLER CORNELIUS 2010-08-19 US claimed
EP-4192614-B1 PROCESS FOR THE PREPARATION OF MICROCAPSULES SYMRISE AG (DE) 2026-05-06 EP disclosed
US-12583833-B2 Enrichment of a diastereomer in Magnolan SYMRISE AG (DE) 2026-03-24 US disclosed
EP-4687810-A1 PREPARATIONS COMPRISING HYDROXY PINACOLONE RETINOATE Symrise AG (DE) 2026-02-11 EP disclosed
EP-4692252-A1 FUNCTIONAL PARTICLE DISPERSION MITSUBISHI PENCIL COMPANY, LIMITED (JP) 2026-02-11 EP disclosed
US-12545851-B2 Fragrances with note of lily of the valley SYMRISE AG (DE) 2026-02-10 US disclosed
US-12453693-B2 Encapsulated fragrance compounds based on natural amino acids SYMRISE AG (DE) 2025-10-28 US disclosed
US-12409433-B2 Microcapsules SYMRISE AG (DE) 2025-09-09 US disclosed
US-20250144589-A1 Method for Producing Microcapsules SYMRISE AG (DE) 2025-05-08 US disclosed
EP-0659179-A1 BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE MERCK & CO. INC. (US) 1995-06-28 EP disclosed
US-5310737-A Benzo-fused lactams that promote the release of growth hormone MERCK & CO., INC. (US) 1994-05-10 US disclosed
WO-1994005634-A1 BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE MERCK & CO., INC. (US) 1994-03-17 WO disclosed
US-5283241-A Animal growth regulators MERCK & CO., INC. (US) 1994-02-01 US disclosed
US-5206235-A Animal growth regulators; stimulants MERCK & CO., INC. (US) 1993-04-27 US disclosed
EP-0513974-A1 Novel benzo-fused lactams that promote the release of growth hormone MERCK & CO. INC. (US) 1992-11-19 EP disclosed
WO-1992016524-A1 BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE MERCK & CO., INC. (US) 1992-10-01 WO disclosed
US-4524017-A Derivatives of norbornanes having hydrocarbon side chains and perfume compositions containing the same NIPPON PETROCHEMICALS CO., LTD. (JP) 1985-06-18 US disclosed
US-4033993-A Cycloalkyl carbonates HENKEL & CIE G.M.B.H. (DT) 1977-07-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12583833-B2 Enrichment of a diastereomer in Magnolan TRPA1, ENO1, ADH1A MAOB 1014/4885LMNA 1005/4885TDP1 3089/4885
US-12453693-B2 Encapsulated fragrance compounds based on natural amino acids SMS, CUTA, SRM MAOB 947/4885LMNA 4455/4885TDP1 4443/4885
US-12545851-B2 Fragrances with note of lily of the valley TRPA1, CDY1; CDY1B, TMEM109 MAOB 230/4885LMNA 2825/4885TDP1 3981/4885
US-12409433-B2 Microcapsules TERT, TTPA, TERB1 MAOB 2112/4885LMNA 2360/4885TDP1 1150/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.