Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | HNF4A | P41235 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8468956 | 0.82 | MTNR1A (0.42) | KMT2AFOLH1PDCD1CD274BACE1 | |
| SCHEMBL4659888 | 0.81 | FOLH1 (0.61) | KMT2AFOLH1PDCD1CD274BACE1 | |
| SCHEMBL20957481 | 0.78 | PDCD1 (0.44) | KMT2APDCD1CD274DPP4MAPK1 | |
| SCHEMBL7562147 | 0.78 | PDCD1 (0.45) | KMT2APDCD1CD274HDAC1HDAC6 | |
| SCHEMBL18143536 | 0.75 | HNF4A (0.58) | KMT2ABACE1TDP1L3MBTL1PTPN1 | |
| SCHEMBL180120 | 0.75 | SMN1; SMN2 (0.47) | KMT2APDCD1CD274BACE1TDP1 | |
| SCHEMBL5033866 | 0.75 | FOLH1 (0.66) | KMT2AFOLH1PDCD1CD274PTGER1 | |
| SCHEMBL26185970 | 0.74 | PTGER4 (0.44) | TDP1L3MBTL1PTGER1PTGER4PTGER3 | |
| SCHEMBL7557382 | 0.73 | DPP4 (0.53) | KMT2AFOLH1PDCD1CD274BACE1 | |
| SCHEMBL31163822 | 0.72 | DPP4 (0.60) | KMT2AFOLH1PDCD1CD274BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991013063-A1 | NEW BENZIMIDAZOLE DERIVATIVES, METHOD FOR PREPARING THEM AND THEIR PHARMACEUTICAL USE | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1991-09-05 | — | — | WO | disclosed |