SCHEMBL9755085

SCHEMBL9755085

CN(C)c1ccc(C2=NC(=O)N=C2c2ccccc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.45
RAB9A P51151 3/20 0.45
NPC1 O15118 2/20 0.45
KDM4E B2RXH2 2/20 0.45
GUSB P08236 1/20 0.45
NOX1 Q9Y5S8 1/20 0.44
HPGD P15428 2/20 0.43
ALDH1A1 P00352 4/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
TSHR P16473 3/20 0.42
CYP1A2 P05177 2/20 0.42
LMNA P02545 1/20 0.42
GLA P06280 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
RECQL P46063 1/20 0.42
HIF1A Q16665 1/20 0.42
HSD17B10 Q99714 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4633787 0.82 MAPT (0.44) MAPTRAB9ANPC1KDM4EHPGD
SCHEMBL9755125 0.81 ALDH1A1 (0.44) MAPTRAB9ANPC1KDM4EGUSB
SCHEMBL15125583 0.77 ALDH1A1 (0.61) MAPTRAB9ANPC1KDM4ENOX1
SCHEMBL2778637 0.77 ALDH1A1 (0.61) MAPTRAB9ANPC1KDM4ENOX1
SCHEMBL5518439 0.76 MAPT (0.36) MAPTRAB9ANPC1KDM4EGUSB
Phosphine SCHEMBL28255440 0.75 ALDH1A1 (0.58) MAPTRAB9ANPC1KDM4ENOX1
Hydrochloric Acid SCHEMBL2861594 0.75 ALDH1A1 (0.58) MAPTRAB9ANPC1KDM4ENOX1
SCHEMBL29239352 0.75 ALDH1A1 (0.58) MAPTRAB9ANPC1KDM4ENOX1
SCHEMBL8195881 0.72 ALDH1A1 (0.40) MAPTRAB9ANPC1ALDH1A1LMNA
SCHEMBL17735817 0.71 ALDH1A1 (0.52) MAPTRAB9ANPC1KDM4ENOX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1991005290-A1 IMPROVED PERSISTENT PHOTOCONDUCTIVE COATING COMPOSITION POLYCHROME CORPORATION (US) 1991-04-18 WO disclosed
US-4960663-A PHOTOCONDUCTOR, PHOTOINITIATOR AND ACTATE OF PHENOLIC HYDROXYL-CONTAINING RESIN DISPERSED IN A RESINOUS MATRIX; XEROGRAPHY; PLATES POLYCHROME CORPORATION (US) 1990-10-02 US disclosed
EP-0385376-A2 Persistent photoconductive coating composition Polychrome Corporation (US) 1990-09-05 EP disclosed
US-4431722-A POLYCYCLIC QUINONE PIGMENT DISPERSED IN A RESIN BINDER AS CHARGE GENERATING LAYER; ANTIFOGGING AGENTS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1984-02-14 US disclosed
US-4033769-A Persistent photoconductive compositions XEROX CORPORATION (US) 1977-07-05 US disclosed
US-3961954-A Acid sensitized charge transfer complexes and cyclic electrostatographic imaging XEROX CORPORATION (US) 1976-06-08 US disclosed
US-3932025-A Imaging system XEROX CORPORATION (US) 1976-01-13 US disclosed