Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 5/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30416768 | 0.74 | SIRT6 (0.50) | SIRT6ELANEDRD2HTR2AHTR1A | |
| SCHEMBL9640183 | 0.73 | SIRT6 (0.47) | SIRT6ACHEELANEDRD4DRD2 | |
| Hydrochloric Acid SCHEMBL9639460 | 0.72 | SIRT6 (0.46) | SIRT6ACHEELANEDRD4DRD2 | |
| SCHEMBL18448567 | 0.68 | SIRT6 (0.43) | SIRT6ACHEELANEPIK3CAMTOR | |
| SCHEMBL29722186 | 0.67 | ELANE (0.48) | SIRT6ACHEELANEDRD4DRD2 | |
| SCHEMBL9755216 | 0.66 | ELANE (0.45) | SIRT6ACHEELANEDRD4DRD2 | |
| SCHEMBL31213085 | 0.65 | DRD2 (0.45) | SIRT6DRD4DRD2HTR2AHTR1A | |
| SCHEMBL18449843 | 0.65 | MAP4K4 (0.45) | SIRT6ACHEELANEDRD4DRD2 | |
| SCHEMBL7149337 | 0.63 | MAPT (0.47) | HTR1ADRD3 | |
| SCHEMBL29816483 | 0.63 | HTR1A (0.56) | DRD2HTR2AHTR1ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991006542-A1 | PHARMACEUTICALLY ACTIVE AMINO-SUBSTITUTED HETEROARYL AMINES | THE UPJOHN COMPANY (US) | 1991-05-16 | — | — | WO | claimed |