Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 18/20 | 0.67 |
| ▸ | CTSD | P07339 | 3/20 | 0.56 |
| ▸ | CTSE | P14091 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14415365 | 0.83 | REN (0.61) | RENCTSDCTSE | |
| SCHEMBL9640485 | 0.82 | REN (0.54) | RENCTSDCTSE | |
| SCHEMBL7351443 | 0.75 | REN (0.64) | RENCTSDCTSE | |
| Hydrochloric Acid SCHEMBL8531652 | 0.74 | CTSD (0.53) | CTSD | |
| SCHEMBL10378904 | 0.74 | POLB (0.54) | RENCTSDCTSE | |
| Hydrochloric Acid SCHEMBL10431267 | 0.73 | CYP3A4 (0.58) | RENCTSDCTSE | |
| Hydrochloric Acid SCHEMBL8613009 | 0.72 | ANPEP (0.59) | CTSD | |
| Hydrochloric Acid SCHEMBL8613014 | 0.72 | ANPEP (0.59) | CTSD | |
| SCHEMBL15532120 | 0.72 | REN (0.81) | RENCTSDCTSE | |
| SCHEMBL30052924 | 0.71 | CTSD (0.64) | RENCTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991006561-A1 | METHOD FOR TREATING HIV AND OTHER RETROVIRUSES AND COMPOUNDS USEFUL THEREFOR | THE UPJOHN COMPANY (US) | 1991-05-16 | — | — | WO | disclosed |