Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 19/20 | 0.64 |
| ▸ | CTSD | P07339 | 2/20 | 0.48 |
| ▸ | CTSE | P14091 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370152 | 0.77 | REN (0.56) | RENCTSDCTSE | |
| SCHEMBL9755323 | 0.77 | REN (0.57) | RENCTSDCTSE | |
| SCHEMBL9755311 | 0.75 | REN (0.67) | RENCTSDCTSE | |
| SCHEMBL11013722 | 0.74 | REN (0.58) | REN | |
| SCHEMBL7351457 | 0.74 | MME (0.42) | — | |
| SCHEMBL9755316 | 0.73 | REN (0.48) | RENCTSDCTSE | |
| SCHEMBL11013919 | 0.73 | REN (0.66) | REN | |
| SCHEMBL11010625 | 0.73 | REN (0.66) | REN | |
| SCHEMBL14415365 | 0.73 | REN (0.61) | RENCTSDCTSE | |
| SCHEMBL7351446 | 0.72 | REN (0.49) | RENCTSDCTSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4894437-A | Novel renin inhibiting polypeptide analogs containing S-aryl-D- or L- or DL-cysteinyl, 3-(arylthio)lactic acid or 3-(arylthio)alkyl moieties | THE UPJOHN COMPANY (US) | 1990-01-16 | — | — | US | claimed |
| EP-0245361-A1 | NOVEL RENIN INHIBITING POLYPEPTIDE ANALOGS CONTAINING S-ARYL-D- OR L- OR DL-CYSTEINYL, 3-(ARYLTHIO)LACTIC ACID OR 3-(ARYLTHIO)ALKYL MOIETIES | THE UPJOHN COMPANY (US) | 1987-11-19 | — | — | EP | claimed |
| WO-1987002986-A1 | NOVEL RENIN INHIBITING POLYPEPTIDE ANALOGS CONTAINING S-ARYL-D- OR L- OR DL-CYSTEINYL, 3-(ARYLTHIO)LACTIC ACID OR 3-(ARYLTHIO)ALKYL MOIETIES | THE UPJOHN COMPANY (US) | 1987-05-21 | — | — | WO | claimed |