Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 16/20 | 0.57 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | CTSE | P14091 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316741 | 0.89 | REN (0.45) | RENCTSDCTSEPSMB5CTSK | |
| SCHEMBL7325297 | 0.80 | REN (0.46) | RENCTSDCTSE | |
| SCHEMBL7370152 | 0.77 | REN (0.56) | RENCTSDCTSE | |
| SCHEMBL7285659 | 0.76 | REN (0.49) | RENCTSDPTPN1 | |
| SCHEMBL7285655 | 0.76 | REN (0.49) | RENCTSDPTPN1 | |
| SCHEMBL10721002 | 0.75 | REN (0.58) | REN | |
| SCHEMBL10903164 | 0.75 | REN (0.58) | REN | |
| SCHEMBL10720995 | 0.75 | REN (0.58) | REN | |
| SCHEMBL10903182 | 0.75 | REN (0.58) | REN | |
| SCHEMBL7323845 | 0.74 | REN (0.58) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991006561-A1 | METHOD FOR TREATING HIV AND OTHER RETROVIRUSES AND COMPOUNDS USEFUL THEREFOR | THE UPJOHN COMPANY (US) | 1991-05-16 | — | — | WO | claimed |