Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8518298 | 0.80 | MTNR1A (0.50) | MTNR1AMTNR1BLMNALTA4HKDM4E | |
| SCHEMBL28263637 | 0.80 | MTNR1A (0.46) | MTNR1AMTNR1BLMNALTA4HKDM4E | |
| SCHEMBL3469518 | 0.77 | MTNR1A (0.50) | MTNR1AMTNR1BLMNALTA4HKDM4E | |
| SCHEMBL9870637 | 0.76 | MTNR1A (0.53) | MTNR1AMTNR1BLMNALTA4HKDM4E | |
| SCHEMBL9870647 | 0.76 | MTNR1A (0.53) | MTNR1AMTNR1BLMNALTA4HKDM4E | |
| SCHEMBL13941995 | 0.75 | MTNR1A (0.49) | MTNR1AMTNR1BLMNALTA4HMAOA | |
| SCHEMBL2505117 | 0.75 | LMNA (0.61) | MTNR1AMTNR1BLMNAMAOAPTGS1 | |
| SCHEMBL257324 | 0.74 | MTNR1A (0.52) | MTNR1AMTNR1BLMNALTA4HKDM4E | |
| SCHEMBL12550266 | 0.74 | MTNR1A (0.52) | MTNR1AMTNR1BLMNALTA4HKDM4E | |
| SCHEMBL28121089 | 0.74 | MTNR1A (0.52) | MTNR1AMTNR1BLMNALTA4HKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991005750-A2 | PROCESS FOR PRODUCING FLUORINATED ORGANIC COMPOUNDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-05-02 | — | — | WO | disclosed |