Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | TPMT | P51580 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DDO | Q99489 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL353837 | 0.87 | THRB (0.46) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL12196883 | 0.82 | POLB (0.49) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL27788176 | 0.81 | TSHR (0.50) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL16982215 | 0.81 | TSHR (0.46) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL14937515 | 0.80 | TSHR (0.53) | POLBAPEX1HTTTDP1TSHR | |
| Methacrylic Acid SCHEMBL9755535 | 0.79 | TPMT (0.45) | TDP1THRBTSHRTPMTALDH1A1 | |
| SCHEMBL29052705 | 0.78 | POLB (0.49) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL10719642 | 0.78 | THRB (0.51) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL11999077 | 0.77 | POLB (0.55) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL20649445 | 0.77 | THRB (0.42) | POLBAPEX1HTTTDP1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3059031-A | — | — | None | — | — | JP | disclosed |
| JP-3059034-A | — | — | None | — | — | JP | disclosed |
| JP-H0359034-A | PRODUCTION OF POLYIMIDE RESIN | HITACHI CHEM CO LTD | 1991-03-14 | — | — | JP | disclosed |
| JP-H0359031-A | POLYIMIDOISOINDOLOQUINAZOLINEDIONE AND PRODUCTION OF ITS PRECURSOR | HITACHI CHEM CO LTD | 1991-03-14 | — | — | JP | disclosed |