SCHEMBL9755646

SCHEMBL9755646

Cn1c2ccccc2c2c(C=O)cccc21

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.52
ALDH1A1 P00352 4/20 0.51
IMPDH2 P12268 1/20 0.51
MAPT P10636 6/20 0.50
HTT P42858 6/20 0.50
LMNA P02545 4/20 0.46
NQO2 P16083 2/20 0.44
NPSR1 Q6W5P4 4/20 0.43
HPGD P15428 1/20 0.43
KDM4E B2RXH2 4/20 0.43
SMN1; SMN2 Q16637 4/20 0.43
POLB P06746 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2C19 P33261 1/20 0.43
NOD2 Q9HC29 1/20 0.42
TDP1 Q9NUW8 2/20 0.42
ATM Q13315 1/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9540071 0.79 ALDH1A1 (0.49) GPR3ALDH1A1IMPDH2MAPTHTT
SCHEMBL9986282 0.78 ALDH1A1 (0.54) ALDH1A1IMPDH2MAPTHTTLMNA
SCHEMBL14313953 0.76 GPR3 (0.71) GPR3ALDH1A1MAPTHTTNQO2
SCHEMBL21298409 0.76 KDM4E (0.55) ALDH1A1IMPDH2LMNAKDM4EPOLB
SCHEMBL9754577 0.76 ALDH1A1 (0.42) ALDH1A1IMPDH2MAPTHTTLMNA
SCHEMBL16376471 0.75 GPR3 (0.62) GPR3ALDH1A1MAPTHTTLMNA
SCHEMBL5022814 0.74 PTGER4 (0.43) ALDH1A1IMPDH2MAPTPOLBL3MBTL1
Acetaldehyde SCHEMBL28007694 0.74 GPR3 (0.76) GPR3ALDH1A1IMPDH2MAPTHTT
SCHEMBL20595409 0.74 KDM4E (0.53) GPR3ALDH1A1MAPTHTTLMNA
SCHEMBL22722810 0.73 HTT (0.53) GPR3ALDH1A1MAPTHTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3197396-A None JP disclosed
JP-H03197396-A PRODUCTION OF ORGANIC CRYSTAL THIN FILM SUMITOMO ELECTRIC IND LTD 1991-08-28 JP disclosed