Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | CXCR4 | P61073 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2925434 | 0.84 | LMNA (0.54) | LMNACHRM2CYP1A2SLC6A4OPRD1 | |
| SCHEMBL9938300 | 0.81 | KDM4E (0.61) | LMNAMEN1KMT2AHRH3KDM4E | |
| SCHEMBL20971765 | 0.78 | CXCR3 (0.57) | SOS1KDM4ESMN1; SMN2 | |
| SCHEMBL22684197 | 0.78 | LMNA (0.44) | LMNACHRM2CYP1A2SLC6A4OPRD1 | |
| SCHEMBL2924537 | 0.77 | KDM4E (0.70) | LMNACHRM2CYP1A2SLC6A4OPRD1 | |
| SCHEMBL2922854 | 0.77 | KDM4E (0.51) | LMNACHRM2CYP1A2SLC6A4OPRD1 | |
| SCHEMBL593144 | 0.76 | ALDH1A1 (0.68) | LMNACYP1A2SLC6A4SIGMAR1MEN1 | |
| SCHEMBL7438574 | 0.76 | ALDH1A1 (0.68) | LMNACYP1A2SLC6A4SIGMAR1MEN1 | |
| SCHEMBL15566396 | 0.76 | SOS1 (0.49) | LMNACHRM2CYP1A2SIGMAR1CXCR4 | |
| Hydrochloric Acid SCHEMBL1238937 | 0.76 | KDM4E (0.68) | LMNACHRM2CYP1A2SLC6A4OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991011463-A1 | ENDOGENOUS BRAIN FACTOR, METHOD FOR OBTAINING IT AND THERAPEUTIC AND DIAGNOSTIC USES THEREOF | INSTITUT PASTEUR (FR) | 1991-08-08 | — | — | WO | disclosed |