Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13024122 | 0.81 | ESR1 (0.60) | ESR1ESR2MEN1KMT2ACYP19A1 | |
| SCHEMBL7915425 | 0.80 | ESR1 (0.53) | ESR1ESR2MEN1KMT2ACYP19A1 | |
| SCHEMBL17548404 | 0.77 | HTR2A (0.48) | ESR1ESR2ALDH1A1HTR2AHTR2C | |
| SCHEMBL17548554 | 0.76 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1HTR2AHTR2C | |
| SCHEMBL4884271 | 0.74 | ESR1 (0.55) | ESR1ESR2MEN1KMT2ACYP19A1 | |
| SCHEMBL29039706 | 0.70 | PTGS2 (0.52) | ESR1ESR2PTGS2KIF11 | |
| SCHEMBL3929385 | 0.69 | ESR1 (0.63) | ESR1ESR2MEN1KMT2ACYP19A1 | |
| SCHEMBL27293850 | 0.69 | ESR1 (0.63) | ESR1ESR2MEN1KMT2ACYP19A1 | |
| SCHEMBL820614 | 0.69 | MAPK14 (0.55) | ESR1ESR2PTGS2HTR2AHTR2C | |
| SCHEMBL7076291 | 0.68 | ESR1 (0.71) | ESR1ESR2PTGS2KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3193762-A | — | — | None | — | — | JP | disclosed |
| JP-H03193762-A | METHYLENE-CROSSLINKED INDOLYL ARYL METHANE COMPOUND | FUJI PHOTO FILM CO LTD | 1991-08-23 | — | — | JP | disclosed |